Volume 53, Number 8, August 2008
Editorial | |
547 | " align="left" valign="top" class="tocTitle">
Lawrence D. Devoe, M.D.
|
|
|
Symposium | |
Gestational Trophoblastic Disease: Presentations from the XIVth World Congress on Gestational Trophoblastic Diseases Ross S. Berkowitz, M.D., and Donald P. Goldstein, M.D., Guest Editors Other articles appeared in the July 2008 issue. |
|
549 | " align="left" valign="top" class="tocTitle">
Laurence A. Cole, Ph.D., Sarah A. Khanlian, M.P.H., and Ernest I. Kohorn, M.Chir., F.R.C.S., F.R.C.O.G.
It is inferred that invasive gestational trophoblastic diseases occur uniquely in humans as a complication of the human generation of high concentrations of the invasion promoter hyperglycosylated chorionic gonadotropin.
|
|
|
558 |
Zoltan Nagymanyoki, M.D., Michael J. Callahan, M.D., Mana M. Parast, M.D., Vilmos Fulop, M.D., Ph.D., Samuel C. Mok, Ph.D., and Ross S. Berkowitz, M.D.
Further study of the adhesion molecules and the immunologic response in CCA may provide important insights into the immunobiology of this neoplastic process.
|
|
|
565 |
Julia E. Palmer, M.D., M.R.C.O.G., Barry W. Hancock, M.D., F.R.C.P.C., F.R.C.R., D.C.H., and John A. Tidy, M.D., F.R.C.O.G.
This study addresses the question of whether older patients with gestational trophoblastic neoplasia in the United Kingdom have a worse prognosis and poorer response to chemotherapeutic regimens than younger women.
|
|
|
575 |
Adrian K. P. Lim, M.D., F.R.C.R., Daksha Patel, D.M.U., Nayna Patel, M.Sc., D.M.U., Katherine Hawtin, M.R.C.P., F.R.C.R., Linda Dayal, B.Sc., S.R.N., Peter Schmid, M.D., Ph.D., Philip Savage, Ph.D., F.R.C.P., and Michael J. Seckl, Ph.D., F.R.C.P.
Magnetic resonance imaging and Doppler ultrasound are complementary investigations of the pelvis in patients with gestational trophoblastic neoplasia; the vascularity of the tumor is better assessed on Doppler ultrasound, and tumor extension and detection are better with magnetic resonance imaging.
|
|
|
579 |
Patr�cia Daniela Paranhos B. Soares, M.D., Ol�via L?cia Nunes Costa, M.D., Ludmila Andrade Costa, M.D., and Izildinha Maest�, Ph.D., M.D.
It is important that strict histologic criteria for gestational trophoblastic disease are used in the assessment of all samples of tubal ectopic gestation.
|
|
|
583 |
Shigeru Sasaki, M.D., Ph.D., and Yasushi Sasaki, M.D., Ph.D.
This diagnostic score should be very useful for comparing the nearly true incidence of choriocarcinoma and survival rate between nations.
|
|
|
589 |
Zoltan Nagymanyoki, M.D., Whitfield B. Growdon, M.D., Jennifer Sarno, M.S., Michael J. Callahan, M.D., Mana M. Parast, M.D., Vilmos Fulop, M.D., Ph.D., Samuel C. Mok, Ph.D., Neil Horowitz, M.D., and Ross S. Berkowitz, M.D.
Further study of this relationship between human chorionic gonadotropin as an angiogenic factor in molar pregnancy and persistent gestational trophoblastic neoplasia may provide important new insights into the biology of gestational trophoblastic diseases and may contribute to the development of novel therapies.
|
|
|
595 |
Ma. Stephanie Fay S. Cagayan, M.D.
In this study, sexual dysfunction was noted to be a common complication of treatment of gestational trophoblastic neoplasia yet was given little attention as compared to other complications.
|
|
|
600 |
Jun-jun Yang, M.D., Yang Xiang, M.D., Xi-run Wan, M.D., and Xiu-yu Yang, M.D.
Gestational trophoblastic neoplasia has varying tendencies toward local invasion and distant metastases because of abnormal growth and proliferation of trophoblastic cells.
|
|
|
608 |
Yan Chen, Ph.D., Haili Qian, Ph.D., Ying Zhang, M.D., Yan Ma, Ph.D., Chen Lin, Ph.D., and Yang Xiang, M.D.
In addition to its role in inhibiting tumor adhesion and invasion, TIMP3 induced apoptosis and inhibited the growth of jeg-3 and bewo.
|
|
|
615 |
Alicia F. C. Okines, M.D., Richard Morris, Ph.D., and Barry W. Hancock, M.D.
Surgery remains an important part of the management of selected cases of gestational trophoblastic neoplasia, and predictive markers of chemotherapy resistance need to be identified to allow such patients to be selected early.
|
|
|
623 |
Li Ma, M.D., Yang Xiang, M.D., Jun Zhao, Ph.D., Fengzhi Feng, M.D., and Xirun Wan, M.D.
We sought to explore the differential protein expression between benign/remitting and malignant-transformed hydatidiform mole, searching for a prognostic biomarker to immediately identify those patients requiring chemotherapy to achieve early diagnosis and early intervention.
|
|
|
629 |
Jin-lin Hou, M.D., Xi-run Wan, M.D., Yang Xiang, M.D., Qing-wei Qi, M.D., and Xiu-yu Yang, M.D.
The traditional presenting signs and symptoms of hydatidiform mole are less frequently present in current patients, especially for severe complications such as pregnancy-induced hypertension and hyperthyroidism.
|
|
|
634 |
Ruangsak Lertkhachonsuk, M.D., and Surang Treratanachat, M.D.
This study examined intrauterine pathology in patients with post-molar gestational trophoblastic neoplasia and hydatidiform mole after suction curettage and evaluated safety profiles of endometrial sampling in this setting.
|
|
|
639 |
S. Sinan �zalp, M.D.
No correlation was found between the fetal outcome and the amount of chemotherapeutic exposure.
|
|
|
643 |
Richard A. Harvey, B.Sc., M.Sc., Ph.D., Howard D. Pursglove, B.Sc., Peter Schmid, M.D., Ph.D., Philip M. Savage, F.R.C.P., Ph.D., Hugh D. C. Mitchell, B.Sc., and Michael J. Seckl, F.R.C.P., Ph.D.
Free hCGbeta-subunit proportion of total hCG measurement can help distinguish placental site trophoblastic tumor from more common forms of gestational trophoblastic disease.
|